Ultra Glutamine

Background:
Immune system suppression is often the result of metabolic stress through injury, illness, or diet (starvation) produce significantly less Glutamine than may be needed for critical bodily processes. An important result of this shortage is that the body breaks down muscle tissue to synthesize the Glutamine it needs for other critical sites. This wastage of skeletal muscle is a major factor in the debilitation of the body and loss of vital energy.

Conjunctively, in the kidney, Glutamine also regulates electrolyte balance and the acid/base balance which affects muscle response. Low reserves result in excessive excretion of calcium, magnesium, potassium, phosphorus and a move to acid balance, again with resulting loss of physical energy.

Overall, low levels of Glutamine, may contribute to tissue wasting, susceptibility to disease, and fatigue.

Purpose of Ultra Glutamine Formula:
To address the consequences of Glutamine deficiencies L-Glutamine is the single largest pool of an amino acid in the body, it also is among the first to be affected by a deficiency of supply. Because of its unique structure (it has two nitrogen atoms) it is utilized for three functions - a fuel, a new body protein, and to synthesize other important compounds and amino acids. Its presence, or lack of, is critical for the proper function of the body - but in particular, skeletal muscle, the digestive system, the immune system and the brain.
Examples of Glutamine need are:

1. Skeletal Muscle. Glutamine has two nitrogen atoms and uniquely acts as a nitrogen shuttle to protect skeletal muscle mass and maintain a positive nitrogen balance in muscle tissue.

2. Immune System. Through another transamination process, it serves the immune system by providing key ingredient for white cell production while at same time inhibiting excessive cytokine production characteristic of autoimmune disorders. The transconversion to Glutathione makes it a significant component in the bodys' own antioxidant arsenal,

3. Digestive System, Glutamine is the main nutrient necessary for intestinal repair. Mucosal cells (enterocytes) utilize Glutamine as their primary energy source for nutrient absorption and for cell regeneration. Low levels will thin the intestinal mucosa and leave it susceptible to bacterial infiltration,

4. Brain. Glutamine is the precursor to inhibitory neurotransmitters (glutamate and GABA), that with decreased levels, is noted with addictions such as alcohol and states such as depression.

Pyridoxine alpha ketoglutarate (PAK) is a combination of Vitamin B-6 and alpha ketoglutarate. In the liver it is converted to pyridoxal phosphate - the biologically active form of B-6. This acts as a coenzyme in the metabolism of protein, carbohydrates, and fats. It is the biological catalyst that provides the enzymatic and energy substrates necessary for effective utilization of L-Glutamine in its many roles.

It is a component for the body's detoxification mechanism, as pyridoxal phosphate it is necessary for the non-oxidative degradation of amino acids through the removal of CO2 and also necessary for the removal of toxic ammonia molecules by combining with glutamic acid to produce Glutamine.
Of equal weight, it is also the enzymatic substrate for the metabolic activity of Glutamine in the examples described above.

Product Description:
This energy enhancing formula is a combination of the amino acid L- Glutamine with the enzymatic and energy substrates found in the nutritional complex of Vitamin B-6 and alpha-ketoglutaric acid, L-Glutamine is a non essential amino acid. It is synthesized by the body in the liver from the intake of food. Increasingly, its functional role has been recognized as so important that it is now considered essential that sufficient amounts be present, making it the "essential nonessential amino acid". The two components of PAK work to increase energy production in the mitochondria by increasing the availability of energy substrates through the citric acid (Krebs energy) cycle. PAK also reduces the accumulation of lactic and pyruvic acids which are built up in muscles during strenuous activity, L-Glutamine and PAK are combined in a 3 to 1 ratio to provide a balance of Glutamine with the necessary quantity of biologically active enzymatic and energy substrate activators to achieve a more complete and robust utilization of its components.

By effectively supplying the necessary nutritional support to address the consequences of diminished Glutamine levels, additional energy reserves can be made available for those who are metabolically stressed. The result is a healthy immune system and better health.

Recommended Dosage:
Dosage is 3 capsules daily on an empty stomach, or directed by a health professional,
Please refer to our Health precautions section before proceeding.

Each three capsules contains:

Nutrient	Dose%	USRDA
L-Glutamine	11000 mg.	*
PAK	1000 mg.
(Pyridoxinc Alpha Ketoglutarate)
Pyridoxine	268 mg.	13,400
Alpha-kctoglutarate	232 mg.	*

* No RDA bas been established for these, nutrients

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